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The Smartest Long-Term GLP-1 Strategy The strongest long-term strategy is not starvation
As GLP-1R mRNA in the aortic tissue was below the level of quantification in both animal models, it seems likely that GLP-1Rs in other tissues, rather than direct action of liraglutide or semaglutide on the vascular bed, contribute to the mechanism of gene regulation
PubMed PMID: 41109426
The Phase 2 data showed 24.2% average body weight reduction over 48 weeks at the 12mg dose
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