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A clinical research study published in the New England Journal of Medicine documented measurable effects on body weight, glycaemic parameters, and cardiovascular outcomes associated with GLP-1 receptor activation at semaglutide-class doses
10.1172/JCI75276 110 SeeleyR
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8,11 The protein adducts formed, specifically those of mitochondrial protein adducts, lead to oxidative injury and hepatocellular necrosis
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