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I know you didn't mention that as an issue, but I feel there is some link between B12, cystic acne, mast cell dysfunction, gastroparesis and probably many other symptoms
Biochem J 425:31325
Storage & Handling: Store unopened vials at controlled room temperature: 20C to 25C (68F to 77F) After first puncture, store under refrigeration: 2C to 8C (36F to 46F) Do not freeze Use aseptic techniques to maintain sterility Discard any unused portion within 28 days of first puncture according to proper laboratory protocols Compliance Notice: This product is sold strictly for research purposes and is not approved for use in humans or animals
This leads to abnormalities in protein production (identified by deranged coagulation) and metabolism by the liver
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