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Physiologia Plantarum 135, 246257
A recent study demonstrated that NLRP3/caspase-1/GSDMD-mediated pyroptosis in fibroblasts is relatively limited compared with that in macrophages, which express high levels of NLRP3, caspase-1 p20 and GSDMD-NT under LPS plus ATP stress, a strong NLRP3 inflammasome activator and pyroptotic trigger
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The most critical advantage of this structural change is ALCAR's ability to efficiently cross the highly selective blood-brain barrier (BBB)
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