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Biomedicines 5:20

Studies show that with consistent effort, most people lose 510% of their starting weight after a year of lifestyle changes alone, which can significantly improve heart health, quality of life, and reduce the risk of type 2 diabetes

10.1038/emboj.2013.204 45 HuchM.DorrellC.BojS

Although direct neo-N-terminal fragments of caspase-1 were not enriched in the TMT-TAILS dataset, potentially due to labeling inefficiencies, we observed significant depletion of peptides spanning the X(PC) cleavage site in the active protease-treated samples, providing strong evidence of on-target cleavage (Extended Data Fig