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One of the limitations of BBB models prepared from stem cell derived vascular endothelial cells is to induce appropriate barrier tightness and BBB characteristics

In the U.S., CMS guidance from March 2024 allows Medicare Part D coverage of AOMs with medically accepted indications, such as diabetes or reducing the risk of major adverse cardiovascular events in patients with established cardiovascular disease

Owing to effects of GLP-1 on the brain, these drugs are showing promise for reducing alcohol consumption and cigarette use

"We have had very preliminary discussions after we signed the Caremark agreement because we couldn't (before) with the manufacturers and they're very promising, but they're early," Briner said