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Neeland IJ et al
IL-4 causes a rapid increase in choline import, phosphocholine production, and PC biosynthesis ( Retnla ( SLC4A7 , choline dehydrogenase ( CHDH ), choline kinase alpha ( CHKA ), choline acetyltransferase ( CHAT ), and genes related to acetylcholine (ACh)-dependent signaling such as the muscarinic ( CHRM1 and CHRM5 ) and nicotinic ( CHRNA7 ) ACh receptors ( Figure 3 )
Schedule: Daily subcutaneous injections for 812 weeks (extend to 16 weeks if research goals require)
GHK-Cu supplies the extracellular matrix remodeling via collagen, glycosaminoglycans and the MMP-TIMP system as well as an antioxidant and growth-factor-inducing component
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