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This results in higher levels of free, biologically active androgens, which can: Increase sebum production by sebaceous glands Promote follicular hyperkeratinisation (abnormal skin cell turnover) Contribute to the inflammatory processes underlying acne lesions When GLP-1 medications facilitate significant weight loss and improve insulin sensitivity, these hormonal disturbances may partially normalise

Many dermatologists now recommend starting with these gentler options first, reserving hydroquinone for cases that dont respond to initial treatment approaches

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According to Truvetas data, people who get prescriptions for these drugs are younger, whiter, and more likely to be female