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Some researchers notice mild bloating, particularly in the first few weeks
Indeed, in rodent models where they lack GLP-1 receptors in the brain, the central anti-inflammatory response is essentially blocked
The STEP (Semaglutide Treatment Effect in People with obesity) 1 trial was a randomized, placebo-controlled trial that evaluated the efficacy of once-weekly subcutaneous (SC) semaglutide 2.4 mg plus lifestyle interventions in adults with obesity without diabetes (n = 1961)
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