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It will be interesting to see how future research addresses the long-term safety and accessibility of these drugs.
Medical Considerations: Semaglutide or Tirzepatide, including micro-dose programs, cannot be prescribed and should not be purchased by individuals with a BMI under 25 (or under 20 for micro-dosing), an eating disorder, diabetes, gallbladder disease, history of drug or alcohol abuse, recent bariatric surgery, pancreatitis, medullary thyroid cancer or a family history of it, diabetic retinopathy, multiple endocrine neoplasia type 2, or those who are pregnant, breastfeeding, or planning to become pregnant
Total time from prescription to approval averages 2 to 3 weeks
Peer-reviewed data specific to intranasal peptide pharmacokinetics is comparatively limited, which is itself a reason this delivery format is an active area of research interest
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