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EPIDEMIOLOGY AND DISEASE BURDEN OF MASLD/MASH MASLD is estimated to impact around 32.4% of adults across the world and is currently considered the leading chronic liver disease globally, with estimates exceeding one billion individuals affected [13,14]

The International Society for Bipolar Disorders (ISBD) Task Force report on antidepressant use in bipolar disorders

In contrast, evidence for GLP-1 modulation and gut microbiome diversity was inconsistent, drawn primarily from small animal experiments or narrative reviews, and appraised as low certainty

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