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Furthermore, fibrotic remodelling within the synovial joint in rheumatoid arthritis and osteoarthritis [2,3] is considered a major driver of chronic pain and loss of mobility

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[15] It occurs when the thyroid produces insufficient thyroid hormones (thyroxine, T4, and triiodothyronine, T3), leading to symptoms such as fatigue, weight gain, cold intolerance, and constipation