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Retatrutide: The Triple Receptor Compound The compound at the center of this shift, retatrutide, hits three receptors at once: GLP-1, GIP, and glucagon
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BP and Cardiovascular Considerations The Phase 3 program documented modest, transient increases in systolic blood pressure (1.9-2.5 mmHg) and diastolic (1.7-1.8 mmHg) in the 4-6 hours after dosing
In those studies, retatrutide appeared to maintain energy expenditure better than calorie restriction alone, even when food intake was matched
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