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In a combination protocol, some researchers theorize that starting at a lower dose (1mg daily) and assessing tolerance before escalating to the full 2mg might reduce the risk of compounding side effects with retatrutide
O.et al (2006)
[7] [19] Proposed mechanisms include affecting GABA levels, blocking voltage-gated sodium channels, inhibiting histone deacetylases, and increasing LEF1
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