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The key pathological hallmarks of AD include amyloid-beta (A) plaque accumulation, neurofibrillary tangles of hyperphosphorylated tau, chronic neuroinflammation, oxidative stress, and mitochondrial dysfunction (Lv et al., 2020)

Diabetes Obes Metab 2017;19:21627.PubMed 66

You may think what you want about vast federal bureaucracies and their inevitable shortcomings and inefficiencies, but the FDA does provide a very powerful and beneficial service in terms of securing a degree of safety and fraud prevention in the manufacture, marketing, and distribution of prescription medications

To further validate the multivalent interactions of D-CuP, SPR analysis was performed to quantify its binding ability to p53 and HDAC7 in comparison with M-CuP