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Dec 29, 2025 Cagrilintide is a long-acting amylin receptor agonist that produces 10-12% body weight loss through mechanisms completely different from GLP-1s - dramatically slowing gastric emptying, suppressing appetite via brain amylin receptors, and reducing postprandial glucose
Pimkova, K
For 26 weeks, participants received either 14 mg of oral semaglutide or placebo once daily
doi:10.1093/infdis/137.5.668
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