Mediation MR analysis suggests that GLP1 RAs may reduce depression and emotionally unstable personality disorder through the mediator of obesity (Figure 8)
Theoretical interactions may occur with anticoagulants (warfarin), antiplatelet agents, immunosuppressants (tacrolimus), and certain statins
Side effects were more common in the oral semaglutide group (16.7%) than in the injection group (4.9%)
CrossRef Efficacy and safety of lobeglitazone added to metformin and sitagliptin combination therapy in patients with type 2 diabetes: A 52week, multicentre, randomized, placebocontrolled, phase III clinical trial EunGyoung Hong, KyungWan Min, SungWan Chun, Choon Hee Chung, Seungjoon Oh, Chang Beom Lee, DongJun Kim, Hye Soon Kim, Ji Oh Mok, Tae Seo Sohn, Jeong Hyun Park, Sung Hee Choi, Sungrae Kim, Sang Soo Kim, Kyu Yeon Hur, Chong Hwa Kim, Young Min Cho, Byung Diabetes, Obesity and Metabolism.2025