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Symptoms of hypoglycaemia include trembling, sweating, confusion, rapid heartbeat, and in severe cases, loss of consciousness
Both studies began recruitment in late 2024 with Ametrine-2 primary completion estimated for June 2027 and study completion for both trials estimated for December 2029, recruiting across 152 locations worldwide including major medical centers in the United States, Europe, Asia, and other regions, though no results are yet available
While no outcome is guaranteed, the tiered structure is clear
PDE5 inhibitors such as sildenafil and tadalafil generally exhibit better tolerability but can cause headache, flushing, dizziness, and visual disturbances due to partial inhibition of PDE6 in the retina (Wallis, 1999
