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The active ingredient, semaglutide, works by mimicking the action of naturally occurring GLP-1, a hormone released by the intestine in response to food intake
During the last decade, reports have arisen of a metabolite produced by gut bacteria digesting L-carnitine (and choline) called TMA
Emergency treatment may include epinephrine (an EpiPen), corticosteroids, or intravenous fluids
The neuroprotective benefit may stem from GLP-1s role in insulin signaling within the brain, where insulin resistance is a recognized early feature of Alzheimers pathophysiology
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