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To achieve comparable effects, oral doses must be 30-50 times higher, creating cost and side effect challenges

Each vial contains 5mg of research material supplied in a sealed laboratory vial with tamper evident protection and individual batch identification for traceability purposes

42 Another RCT studied cyano-B12, 1500 g three times per day for 2 weeks (route not reported), in patients with seasonal affective disorder and found no improvements in either the B12 or the placebo group

This often manifests as slight changes in stubborn fat areas, increased definition in certain areas, or measurable changes on body composition assessments