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XX wieku jako selektywny agonista receptorw grelinowych, badany w kontekcie farmakologii endokrynologicznej i regulacji osi GHIGF-1
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Metformin is FDA-approved, widely studied, and does not carry the same side effects as GLP-1 medications
This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells
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