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Dec 6 2016;7(49):80262-80274
While previous studies have highlighted the significance of DDX3X in lung cancer progression [22], and small molecule inhibitors such as RK-33 have been developed for treating lung cancer [23], no clinical trials involving DDX3X inhibitors have been initiated thus far
Typical workflows include fibroblast or keratinocyte culture assays for gene expression and proliferation readouts, accelerated stability studies in candidate base formulations, and side-by-side comparison against alternative peptide chemistries
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