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For these patients, the POTS symptoms are part of a complex cascade where genetic vulnerability, environmental toxic exposure (such as mold), and chronic inflammation lead to a breakdown of the blood-brain barrier and the autonomic-immune axis.3 Advocating for a new diagnostic standard of care requires the implementation of an integrative workflow that addresses the airway-centered and neurological roots of POTS

Foretz M, Guigas B, Bertrand L, Pollak M, Viollet B (2014) Metformin: from mechanisms of action to therapies

A few may support insurance coverage, which can help lower your out-of-pocket costs

10.1155/2019/9437043 127 SunX.NiuX.ChenR.HeW.ChenD.KangR.et al (2016a)