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New England Journal of Medicine , 357(23), 2359-2370

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7,8 The physiological impact of phytoestrogens is further modified by gut microbiota composition, habitual intake, life stage, and baseline endogenous hormone levels, resulting in heterogeneous responses across individuals

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When compared to other drugs in the database, the medication was associated with an increased risk of medullary thyroid cancer, gastrointestinal issues, diabetic retinopathy, biliary cholic, and pancreatitis

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Those are organism-level endpoints requiring controlled human trials, most of which have not been run for this compound, and none of them is established for research material or claimed here

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