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A missense mutation in the amine oxidase domain of KDM1A has been reported in patients exhibiting mixed features of Kabuki syndrome (KABUK1) and KBG syndrome (KBGS
For example, because the plasma protein binding of valproate is concentration dependent, the free fraction increases from approximately 10% at 40 mcg/mL to 18.5% at 130 mcg/mL
PMID: 29543316
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