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Theres growing evidence in animal models that the drugs make it through the blood-brain barriera protective membrane surrounding most of the organby penetrating leaky areas, such as the NTS

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The concern is that it could induce formation of a melanoma or excite an already existing melanoma akin to pouring kerosene on a flame

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doi: 10.3389/fendo.2022.1004044 73 SyedYY

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