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This ability to mitigate inflammation without the gastrointestinal risks associated with traditional nonsteroidal anti-inflammatory drugs (NSAIDs) makes it a potentially valuable alternative for pain and inflammation management during recovery
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Mechanism of Action: It works by promoting angiogenesis (the formation of new blood vessels), reducing inflammation, and enhancing tissue repair (Zhao et al., 2020)
Starting low and escalating every four weeks gives your GI system time to adapt
Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau
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