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After 72 weeks, patients who received up to 6 mg of orforglipron averaged a weight loss of 5.5%, those who received 12 mg averaged 7.8%, and those who received 36 mg averaged 10.5%, while the placebo group averaged just 2.2%
The Semaglutide dose is commonly increased to 7 mg, then to 14 mg
No, it is not safe or recommended to take semaglutide and tirzepatide together, or to alternate them on a weekly basis
Gastrointestinal side effects are the defining tolerability issue for the entire incretin class, and both drugs share that profile
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