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This dysfunction affects not only the endothelial cells of the coronary vessels but more crucially those in the intramyocardial capillaries and endocardium, where they interact directly with adjacent cardiomyocytes [12]

Distribution studies using radiolabeled [3H]BPC-157 demonstrate rapid and widespread tissue distribution following systemic administration

Nanomedicine platforms can be designed to selectively target MDSCs based on their surface receptor expression or metabolic vulnerabilities, thereby reducing systemic immunosuppression while preserving beneficial myeloid populations (32, 33)

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