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Unlike where LDL internalization (mediated via the LDL receptor) results in a reduction in LDL receptor expression, through the effects of intracellular cholesterol on the activity of SREBP, macrophage internalization of oxLDL results in increased synthesis of FAT/CD36
Rotem A, Janzer A, Izar B, Ji Z, Doench JG, Garraway LA, et al
To close this efficacy gap, Novo Nordisk is developing a next-generation, high-dose oral semaglutide pill
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