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Why Semaglutide might leave you feeling drained Reduced caloric intake Semaglutide promotes weight loss by suppressing your appetite

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Studies using GIP-Cre mice have demonstrated that GIP receptors are expressed in key brain regions involved in feeding regulation, including the ARC, paraventricular nucleus (PVN), and DMH of the hypothalamus, as well as the area postrema (AP) of the medulla [31]

Though a B12 deficiency can explain some of her findings, this patient continued to worsen despite B12 supplementation, and normalization of her B12 level suggests her presentation cannot be entirely attributed to vitamin B12 deficiency