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GH promotes the breakdown of triglycerides in fat cells, releasing fatty acids for energy use
Cell 82, 22152227
Gclm KO mice also exhibit constitutive activation of liver AMP-activated protein kinase (AMPK) pathway and nuclear factor-erythroid 2related factor 2 target genes, and show enhanced ethanol clearance, altered hepatic lipid profiles in favor of increased levels of polyunsaturated fatty acids and concordant changes in expression of genes associated with lipogenesis and fatty acid oxidation
In vitro Drug Release To evaluate the drug release behavior, 2 mg amount of GCMMR was added into 2 mL of phosphate buffer solution at different pH values (7.4 and 5.0) in the presence or absence of GSH (10mM) and incubated at 37C in a shaking bath
