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~5-fold potency at GIPR relative to native GIP
Allergic reactions , though rare, represent the most immediately concerning complication
Here's what animal research suggests: Documented Interactions (Animal Studies): NSAIDs (ibuprofen, etc.): Protective : BPC-157 prevented 80-90% of NSAID-induced stomach ulcers in rats (Sikiric et al., 1997) Alcohol : Protective : Reduced alcohol-induced damage to stomach and liver
While previous studies have shown that CNS GABAergic neurons are necessary for the food intake- and body weight-reducing effects of GIPR agonists 5,11 , the anatomic region that underlies these effects remains unknown
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