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1998 Apr;30(2):159-68
Wegovy is administered as a once-weekly subcutaneous injection, with a dose-escalation schedule over 16 weeks to minimise gastrointestinal side effects
The clinical threshold, then, is not simply "this is bothering me." It is: has the symptom persisted beyond three weeks of consistent use at a stable dose, with injection timing already optimized to morning administration, and is it producing objective functional harm
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