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Exenatide treatment ameliorates these morphological alterations and inhibits the mitochondrial apoptotic pathway by suppressing cytochrome c release and favorably modulating the expression of pro-apoptotic (Bax, caspase-3) and anti-apoptotic (Bcl-2) proteins, thereby protecting RGC-5 cells from hyperglycemic injury [43]
What Is Tirzepatide and How Does It Work Tirzepatide is a once-weekly injectable medication that works by activating two hormone receptors simultaneously: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor
