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BBB studies have evolved to assess the BBB based on neuroimaging evidence, allowing the calculation of cross-BBB contrast leakage in every voxel of the brain
At best, it may serve as one piece of a larger, clinician-guided plan, but it should never be treated as a substitute for the fundamentals
No regulatory body Health Canada, the FDA, the EMA, the TGA, or any equivalent has approved DSIP as a drug for human or veterinary use
This fits squarely within the evolving toolkit used in translational metabolic studies
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