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Timing relative to sleep and fasting state significantly affects GH response

In addition, GLP-1RA can not only inhibit the PI3K/Akt signaling pathway after activating GLP-1R (13) but also downregulate the expression levels of Cyclin A2 and Cyclin D1,which are markers of cell proliferation related to downstream pathways (95)

M., Russo, G., Leonetti, F., et al