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Key Takeaways Diverticulitis happens when pouches in the colon become infected or inflamed, causing symptoms like pain and fever
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The first hypothesis suggests that excessive nutrient intake leads to the accumulation of misfolded or unfolded proteins in the endoplasmic reticulum, triggering the activation of the unfolded protein response pathway (UPR), which leads to an enhanced expression of pro-inflammatory cytokines [66,67,68,69,70,71]
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