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Shrunken mitochondria with condensed ruptured outer membranes as well as vestigial cristae are a physical hallmark of ferroptosis [24]

In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12

VacA elevates ROS levels, and the antioxidant N-acetyl-L-cysteine abrogates this effect, consequently suppressing autophagy [55]

Dosage: 20 to 40 mcg per day Frequency: Once daily Administration: Subcutaneous or intramuscular injection Timing: Post-workout on training days, morning on rest days Cycle length: 4 to 6 weeks Time off: Equal to time on (4-6 weeks minimum) Starting at the lower end of this range allows you to gauge how your body responds before increasing dosage