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Although reactive electrophiles such as chloroacetamides are generally considered to be promiscuous in target binding, we demonstrated here using a BODIPY-labelled analogue that the chloroacetamide-based GSTO1 inhibitor C1-27 exhibited a low degree of nonspecific reactivity
To our knowledge, this is the first case of an OC secondary to an acquired hypothyroidism (after TT)
Feig DI, Soletsky B, Johnson RJ
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