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Additionally, tirzepatide 15 mg had the lowest number needed to treat (NNT) (Supplementary Material Table S10) across all weight reduction thresholds, where an additional patient achieving 5%, 10%, 15% or 20% weight reduction would be observed if treating 1.46, 1.31, 1.39 or 1.60 patients, respectively, with tirzepatide 15 mg rather than placebo

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Decision tree for use of GLP-1 receptor agonists indicated for weight control in patients with obesity or excess weight with comorbidities

We want to preserve that muscle as you lose weight