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GIP has been shown to decrease food intake while blunting the metabolic adaptive responses that usually occur with calorie restriction resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids

Growth Hormone CJC-1295 is essentially a GHRH analog, one stabilized to extend the hormones half-life, while ipamorelin mimics ghrelin to ramp up GH pulses

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