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To view digital features for this article go to Introduction Obesity (defined as a body mass index [BMI] 30 kg/m 2 in adults [1]) is a major health concern in the USA [2] and is associated with multiple complications, including cardiovascular disease, type 2 diabetes, and osteoarthritis [3,4,5,6,7,8]

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The name reflects the three amino acids that form the peptide structure: Glycine Histidine Lysine Although GHK itself is biologically active, its most studied and therapeutically relevant form is GHK-Cu, which is formed when the peptide binds with a copper ion

That said, it is important to be transparent: there are no large-scale randomized controlled trials proving that lipotropic injections alone produce significant weight loss