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Future clinical studies are essential to validate these promising benefits and to optimize the formulations for widespread clinical use
At concentrations as low as 0.11 ng/mL, endotoxins can activate innate immune pathways in mammalian cells including NF-B and inflammasome signaling which directly confound any study involving cytokine release, cell viability, differentiation, or proliferation
A preparation carrying excess copper contains a loosely bound, redox-active metal pool that is not chemically equivalent to the complex and is the most likely source of artifacts in a culture experiment
Acknowledgements We thank the doctors, nurses, and technicians for their dedicated work during the study at the Department of Endocrinology and Metabolism in Peking University Peoples Hospital
