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When glutathione levels are increased in the body, it disrupts the production of melanin by inhibiting tyrosinase activity
Yet human studies report effects that take an hour to kick in and linger for up to 20 hours
doi: 10.1017/s0007114599001282 85 SchomburgLSchweizerU
Moreover, chronic hyperglycemia leads to increased PKC activation via increased de novo synthesis of DAG, which activates multiple PKC isoforms in diabetic platelets, particularly PKC2 and PKC (Kimura et al., 2001)
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