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Grand challenges in pharmaceutical research series: ridding the cold chain for biologics
N Engl J Med 387(12):10891098 Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, Brar R, Baker C, Gluckman TJ et al (2024) Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity
Diamant M, Nauck MA, Shaginian R, et al
Purpose-built for physicians Human, exendin-based GLP-1 receptor agonists similarly reduce CV, renal risk in diabetes A pooled study assessing trials of eight GLP-1 receptor agonists showed all reduce risk for a combined endpoint of major adverse cardiovascular events, regardless of structural homology to human GLP-1, as well as individual CV components
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