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A warning about compounded semaglutide: the FDA does not approve compounded versions of GLP-1s, and the agency has issued specific warnings about safety risks in 2026

Semaglutide brands like Wegovy, Ozempic, and oral Rybelsus appear in obesity and type 2 diabetes trials

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For those weighing retatrutide against other options, the semaglutide vs tirzepatide comparison provides useful context, as does the retatrutide vs tirzepatide dosage chart for side-by-side dose analysis