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7 One of the most notable antidiabetic agents, metformin, which is classified as a biguanide, is approved for use in type 2 diabetes patients aged 10 years and older and has several off-label uses, including polycystic ovary syndrome, prevention of type 2 diabetes, antipsychotic-induced weight gain, and treatment of gestational diabetes
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While doing so, he chanced to meet the lead chemist of another laboratory, John Pisano, who had a passion for seeking out new and interesting examples of a specific kind of hormone, called a peptide, in animal venoms
Current evidence relies mostly on laboratory and animal studies, while controlled human data remains limited
