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This slowed motility, combined with reduced food intake and often lower fiber and fluid consumption, creates the conditions for constipation
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Thioredoxin-related transmembrane protein 1 (TMX1) interacts with SERCA2b to enhance ATP production in mitochondria through the regulation of ER-mitochondrial contacts and Ca 2+ flux at MAMs, providing a foundation for combating tumors via mitochondria-ER crosstalk (Raturi 2016)
Giuliano F, Clment P, Droupy S, Alexandre L, Bernab J
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