However, theyre not appropriate for pregnant or breastfeeding women, women trying to become pregnant, and people with a history of pancreatitis, certain cancers, some gastrointestinal conditions, or certain kidney diseases
Any severe abdominal pain lasting more than a few hours warrants urgent medical assessment
J Clin Invest 122:388402 Lan H, Vassileva G, Corona A, Liu L, Baker H, Golovko A, Abbondanzo SJ, Hu W, Yang S, Ning Y, Del Vecchio RA, Poulet F, Laverty M, Gustafson EL, Hedrick JA, Kowalski TJ (2009) GPR119 is required for physiological regulation glucagon-like peptide-1 secretion but not for metabolic homeostasis
Oxidative stress (formulated in Harman's free radical theory of aging) is also thought to contribute to the process